# OnCo record dtx1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/dtx1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "dtx1" ;
  schema:name "DTX1"@en ;
  schema:alternateName "deltex E3 ubiquitin ligase 1"@en, "E3 ubiquitin-protein ligase DTX1"@en, "hDx-1"@en, "RNF140"@en, "DTX1" ;
  schema:description "DTX1 (E3 ubiquitin-protein ligase DTX1) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Diffuse large B-cell lymphoma and Chronic lymphocytic leukaemia."@en ;
  schema:url <https://onco.cc/targets/dtx1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3060>, <https://www.uniprot.org/uniprotkb/Q86Y01/entry>, <https://www.ncbi.nlm.nih.gov/gene/1840>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135144> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3060>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000135144>, <https://www.uniprot.org/uniprotkb/Q86Y01/entry>, <https://www.ncbi.nlm.nih.gov/gene/1840> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/cll/> .
