# OnCo record dynamic (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/dynamic/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "dynamic", "ACTRN12615000381583" ;
  schema:name "DYNAMIC"@en ;
  schema:description "Showed that a blood test can safely halve the number of colon cancer patients given chemotherapy after surgery."@en ;
  schema:url <https://onco.cc/trials/dynamic/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://www.nejm.org/doi/full/10.1056/NEJMoa2200075> ;
  onco:status "positive" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/> ;
  onco:terms <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/de-escalation/> ;
  onco:trials <https://onco.cc/trials/dynamic-iii/>, <https://onco.cc/trials/altair/>, <https://onco.cc/trials/circulate-us/>, <https://onco.cc/trials/quasar/> ;
  onco:people <https://onco.cc/people/jeanne-tie/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tie-ctdna-minimal-residual-disease-stage-ii-colon-sci-transl-med-2016/>, <https://onco.cc/key-papers/paper-reinert-ctdna-ultradeep-sequencing-colorectal-jama-oncol-2019/>, <https://onco.cc/key-papers/paper-dynamic-nejm-2022/>, <https://onco.cc/key-papers/paper-dynamic-nat-med-2025-update/> .