# OnCo record eclipse-subclone-ctdna (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/eclipse-subclone-ctdna/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "eclipse-subclone-ctdna" ;
  schema:name "ECLIPSE (subclone tracking from ctDNA)"@en ;
  schema:alternateName "ECLIPSE"@en, "ECLIPSE subclone deconvolution"@en ;
  schema:description "A research method from the TRACERx lung cancer study that estimates which branches of a tumour's family tree are present in a blood sample, but only when there is enough tumour DNA in the blood."@en ;
  schema:url <https://onco.cc/technologies/eclipse-subclone-ctdna/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41586-023-05776-4> ;
  onco:status "emerging" ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/clonal-evolution-tracking/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/mrd/> ;
  onco:trials <https://onco.cc/trials/tracerx/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-subclone-attribution-residual-disease/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-abbosh-tracerx-ctdna-relapse-nature-2023/>, <https://onco.cc/key-papers/paper-abbosh-phylogenetic-ctdna-lung-cancer-nature-2017/> .