# OnCo record eclipse (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/eclipse/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "eclipse", "NCT02004262" ;
  schema:name "ECLIPSE (GVAX pancreas and CRS-207)"@en ;
  schema:alternateName "ECLIPSE study"@en, "GVAX/CRS-207 phase 2b"@en ;
  schema:description "ECLIPSE was the randomised test of the Johns Hopkins pancreatic cancer vaccine strategy, a whole-cell GVAX vaccine followed by a Listeria vector carrying mesothelin; after promising early results it did not beat chemotherapy, with survival of 3.7 months against 4.6, and the programme ended."@en ;
  schema:url <https://onco.cc/trials/eclipse/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02004262>, <https://doi.org/10.1158/1078-0432.CCR-18-2992> ;
  onco:status "negative" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/metastatic-pdac/> ;
  onco:technologies <https://onco.cc/technologies/shared-antigen-vaccine/> ;
  onco:targets <https://onco.cc/targets/mesothelin/> ;
  onco:drugs <https://onco.cc/drugs/cyclophosphamide/> ;
  onco:institutions <https://onco.cc/institutions/johns-hopkins/> ;
  onco:terms <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/pancreatic-failed-programmes/> ;
  onco:trials <https://onco.cc/trials/amplify-7p/>, <https://onco.cc/trials/autogene-cevumeran-phase-1/> .