# OnCo record egfr-bispecific-plus-pd1-hnscc (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/egfr-bispecific-plus-pd1-hnscc/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "egfr-bispecific-plus-pd1-hnscc" ;
  schema:name "EGFR-directed bispecific + PD-1 blockade"@en ;
  schema:description "Pairing a new EGFR antibody with immunotherapy tripled the response rate seen with immunotherapy alone in early trials."@en ;
  schema:url <https://onco.cc/pairings/egfr-bispecific-plus-pd1-hnscc/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06525220>, <https://clinicaltrials.gov/study/NCT06788990> ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/petosemtamab/>, <https://onco.cc/drugs/ficerafusp-alfa/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:trials <https://onco.cc/trials/liger-hn1/>, <https://onco.cc/trials/fortifi-hn01/> ;
  onco:pairs <https://onco.cc/drugs/petosemtamab/>, <https://onco.cc/drugs/pembrolizumab/> .