# OnCo record egfr-exon-19-deletion (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/egfr-exon-19-deletion/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "egfr-exon-19-deletion" ;
  schema:name "EGFR exon 19 deletion"@en ;
  schema:alternateName "EGFR ex19del"@en, "exon 19 deletion"@en, "EGFR del19"@en, "E746_A750del"@en, "EGFR exon 19 del"@en, "classical EGFR mutation"@en ;
  schema:description "An exon 19 deletion removes a few amino acids from the EGFR kinase and leaves it switched on. With L858R it makes up about 85 percent of EGFR-mutant lung cancer and is the classic gate for osimertinib and the other EGFR inhibitors."@en ;
  schema:url <https://onco.cc/biomarkers/egfr-exon-19-deletion/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e81b4a7-b971-45e1-9c31-29cea8c87ce7>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1466c070-9f97-4fa4-a955-6a6b59981fb8> ;
  onco:tag "biomarker", "egfr" ;
  onco:related <https://onco.cc/biomarkers/egfr-l858r/>, <https://onco.cc/biomarkers/egfr-t790m/>, <https://onco.cc/biomarkers/egfr-exon-20-insertion/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/osimertinib/>, <https://onco.cc/drugs/erlotinib/>, <https://onco.cc/drugs/gefitinib/>, <https://onco.cc/drugs/afatinib/>, <https://onco.cc/drugs/dacomitinib/>, <https://onco.cc/drugs/amivantamab/>, <https://onco.cc/drugs/lazertinib/>, <https://onco.cc/drugs/cobas-egfr-mutation-test/>, <https://onco.cc/drugs/therascreen-cdx/>, <https://onco.cc/drugs/oncomine-dx-target-test/>, <https://onco.cc/drugs/foundationone-cdx/>, <https://onco.cc/drugs/guardant360-cdx/> ;
  onco:terms <https://onco.cc/terms/egfr-exon19-l858r/>, <https://onco.cc/terms/egfr-mutation-subtypes/>, <https://onco.cc/terms/ngs/> .