# OnCo record egfr-t790m (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/egfr-t790m/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "egfr-t790m" ;
  schema:name "EGFR T790M"@en ;
  schema:alternateName "T790M"@en, "EGFR T790M mutation"@en, "gatekeeper mutation EGFR"@en, "EGFR exon 20 T790M"@en ;
  schema:description "T790M is the gatekeeper mutation that lung cancers acquire to escape first- and second-generation EGFR inhibitors. Finding it, in tissue or blood, is the historic gate for osimertinib after an earlier EGFR drug."@en ;
  schema:url <https://onco.cc/biomarkers/egfr-t790m/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e81b4a7-b971-45e1-9c31-29cea8c87ce7> ;
  onco:tag "biomarker", "egfr", "resistance" ;
  onco:related <https://onco.cc/biomarkers/egfr-exon-19-deletion/>, <https://onco.cc/biomarkers/egfr-l858r/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/osimertinib/>, <https://onco.cc/drugs/cobas-egfr-mutation-test/> ;
  onco:terms <https://onco.cc/terms/gatekeeper-mutation/>, <https://onco.cc/terms/egfr-mutation-subtypes/>, <https://onco.cc/terms/c797s/> .