# OnCo record entpd1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/entpd1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "entpd1" ;
  schema:name "CD39 (ENTPD1)"@en ;
  schema:alternateName "CD39"@en, "NTPDase-1"@en, "ectonucleoside triphosphate diphosphohydrolase 1"@en, "ENTPD1" ;
  schema:description "CD39 is the first of two enzymes that turn the ATP spilt by dying tumour cells into adenosine, which sedates T cells. Blocking it keeps the ATP alarm ringing; one antibody has completed phase 2 in pancreatic cancer."@en ;
  schema:url <https://onco.cc/targets/entpd1/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3363>, <https://www.uniprot.org/uniprotkb/P49961/entry>, <https://www.ncbi.nlm.nih.gov/gene/953>, <https://clinicaltrials.gov/study/NCT06119217> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3363>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000138185>, <https://www.uniprot.org/uniprotkb/P49961/entry>, <https://www.ncbi.nlm.nih.gov/gene/953> ;
  onco:related <https://onco.cc/targets/cd73-adenosine/>, <https://onco.cc/targets/adora2a/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .