# OnCo record ep4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ep4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ep4" ;
  schema:name "EP4 (PTGER4)"@en ;
  schema:alternateName "EP4"@en, "prostaglandin E receptor 4"@en, "EP4 receptor"@en, "PTGER4" ;
  schema:description "EP4 is one of the receptors for prostaglandin E2, a signal many tumours release that quietens the immune cells around them. EP4 blockers are meant to lift that suppression, and two are in early trials, one with pembrolizumab."@en ;
  schema:url <https://onco.cc/targets/ep4/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9596>, <https://www.uniprot.org/uniprotkb/P35408/entry>, <https://www.ncbi.nlm.nih.gov/gene/5734>, <https://doi.org/10.1080/2162402X.2017.1338239> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9596>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000171522>, <https://www.uniprot.org/uniprotkb/P35408/entry>, <https://www.ncbi.nlm.nih.gov/gene/5734> ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:drugs <https://onco.cc/drugs/inv-1120/>, <https://onco.cc/drugs/dt-9081/> .
