# OnCo record er-pr-negative-threshold (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/er-pr-negative-threshold/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "er-pr-negative-threshold" ;
  schema:name "ER and PR negative under 1 percent (the triple-negative threshold, and ER-low)"@en ;
  schema:alternateName "ER-negative under 1 percent"@en, "ER Low Positive"@en, "ER-low breast cancer"@en, "ER 1 to 10 percent"@en, "Hormone receptor-negative threshold"@en, "PR-negative"@en ;
  schema:description "A breast cancer counts as oestrogen receptor negative when fewer than 1 in 100 of its cells stain for the receptor, and the same rule applies to progesterone receptor. Tumours with 1 to 10 percent staining are labelled ER low positive, but they behave like triple-negative cancers and in some countries are treated as such."@en ;
  schema:url <https://onco.cc/terms/er-pr-negative-threshold/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Estrogen_receptor_test> ;
  schema:citation <https://doi.org/10.1200/jco.19.02309>, <https://www.nice.org.uk/guidance/ng101/chapter/Recommendations>, <https://doi.org/10.1038/s41523-022-00448-4>, <https://doi.org/10.1038/s41523-021-00308-7>, <https://doi.org/10.1016/j.lanepe.2024.100886> ;
  onco:tag "breast", "tnbc" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/tnbc-early/> ;
  onco:terms <https://onco.cc/terms/her2-low/>, <https://onco.cc/terms/pcr/> .