# OnCo record erbb4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/erbb4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "erbb4" ;
  schema:name "HER4 (ERBB4)"@en ;
  schema:description "The fourth member of the HER family, hit by the irreversible pan-HER inhibitors afatinib, dacomitinib and neratinib along with EGFR and HER2. It has no approved drug of its own, and its role in cancer is less clear than that of its siblings."@en ;
  schema:url <https://onco.cc/targets/erbb4/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/ERBB4>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3432>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000178568>, <https://www.uniprot.org/uniprotkb/Q15303/entry>, <https://www.ncbi.nlm.nih.gov/gene/2066> ;
  schema:citation <https://www.uniprot.org/uniprotkb/Q15303/entry> ;
  schema:alternateName "ERBB4" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1993"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:drugs <https://onco.cc/drugs/afatinib/>, <https://onco.cc/drugs/dacomitinib/>, <https://onco.cc/drugs/neratinib/> .