# OnCo record ercc2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ercc2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ercc2" ;
  schema:name "ERCC2"@en ;
  schema:alternateName "ERCC excision repair 2, TFIIH core complex helicase subunit"@en, "General transcription and DNA repair factor IIH helicase subunit XPD"@en, "EM9"@en, "MGC102762"@en, "MGC126218"@en, "MGC126219"@en, "ERCC2" ;
  schema:description "ERCC2 (General transcription and DNA repair factor IIH helicase subunit XPD) is a gene that drives cell growth when it is altered. The public catalogues list it as a drug target, an oncogene driver, a biomarker and a DNA repair gene, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Bladder & urothelial cancer, Skin cancer, Colorectal cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/ercc2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3434>, <https://www.uniprot.org/uniprotkb/P18074/entry>, <https://www.ncbi.nlm.nih.gov/gene/2068>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104884> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "oncogene" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3434>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104884>, <https://www.uniprot.org/uniprotkb/P18074/entry>, <https://www.ncbi.nlm.nih.gov/gene/2068> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/osteosarcoma/> .