# OnCo record ercc3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ercc3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ercc3" ;
  schema:name "ERCC3"@en ;
  schema:alternateName "ERCC excision repair 3, TFIIH core complex helicase subunit"@en, "General transcription and DNA repair factor IIH helicase/translocase subunit XPB"@en, "BTF2"@en, "RAD25"@en, "Ssl2"@en, "ERCC3" ;
  schema:description "ERCC3 (General transcription and DNA repair factor IIH helicase/translocase subunit XPB) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a drug target, a tumour suppressor, a biomarker and a DNA repair gene, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Cervical cancer, Skin cancer, Ovarian cancer and 3 more."@en ;
  schema:url <https://onco.cc/targets/ercc3/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3435>, <https://www.uniprot.org/uniprotkb/P19447/entry>, <https://www.ncbi.nlm.nih.gov/gene/2071>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163161> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3435>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000163161>, <https://www.uniprot.org/uniprotkb/P19447/entry>, <https://www.ncbi.nlm.nih.gov/gene/2071> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/> .