# OnCo record esm3 (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/esm3/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "esm3" ;
  schema:name "ESM3 (EvolutionaryScale)"@en ;
  schema:description "ESM3 is a generative protein model that designed a working fluorescent protein far from any natural sequence."@en ;
  schema:url <https://onco.cc/technologies/esm3/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.ads0018> ;
  onco:status "emerging" ;
  onco:tag "foundation-model", "protein-design" ;
  onco:sections <https://onco.cc/fronts/drug-discovery/>, <https://onco.cc/fronts/ai-computation/> ;
  onco:technologies <https://onco.cc/technologies/ai-drug-design/> ;
  onco:companies <https://onco.cc/companies/evolutionaryscale/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-hayes-science/> .