# OnCo record espac-1 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/espac-1/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "espac-1" ;
  schema:name "ESPAC-1"@en ;
  schema:alternateName "ESPAC1"@en, "European Study Group for Pancreatic Cancer trial 1"@en ;
  schema:description "ESPAC-1 is the 2004 trial that made chemotherapy after pancreatic cancer surgery standard and pushed radiotherapy out: five-year survival was 21 percent with chemotherapy against 8 percent without, while chemoradiotherapy lowered it from 20 to 10 percent."@en ;
  schema:url <https://onco.cc/trials/espac-1/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa032295> ;
  onco:status "mixed" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/resectable-pdac/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/terms/chemoradiation/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/leucovorin/> ;
  onco:institutions <https://onco.cc/institutions/cruk/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/terms/pancreatic-failed-programmes/> ;
  onco:trials <https://onco.cc/trials/espac-3/>, <https://onco.cc/trials/espac-4/>, <https://onco.cc/trials/conko-001/> .