# OnCo record extranodal-extension (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/extranodal-extension/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "extranodal-extension" ;
  schema:name "Extranodal extension (ENE)"@en ;
  schema:alternateName "ENE"@en, "extranodal extension"@en, "extracapsular extension"@en, "extracapsular spread"@en, "extracapsular nodal spread"@en, "ECS"@en, "ENE-positive"@en, "ENE-negative"@en, "pathological extranodal extension"@en, "radiological extranodal extension"@en, "rENE"@en, "major ENE"@en, "minor ENE"@en ;
  schema:description "Extranodal extension means cancer in a lymph node has burst through the node's capsule into the surrounding fat; in head and neck cancer it is the single finding after surgery that most often turns radiotherapy into chemoradiotherapy, and in HPV-negative disease it moves the stage up."@en ;
  schema:url <https://onco.cc/terms/extranodal-extension/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  onco:related <https://onco.cc/terms/lymph-node/>, <https://onco.cc/terms/resection-margins/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/terms/radiotherapy/>, <https://onco.cc/terms/hpv-status/>, <https://onco.cc/terms/depth-of-invasion/>, <https://onco.cc/terms/perineural-invasion/> ;
  onco:cancers <https://onco.cc/cancers/oral-cavity-cancer/>, <https://onco.cc/cancers/oral-tongue-cancer/>, <https://onco.cc/cancers/buccal-mucosa-cancer/>, <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/>, <https://onco.cc/cancers/hpv-positive-oropharyngeal-cancer/>, <https://onco.cc/cancers/salivary-duct-carcinoma/>, <https://onco.cc/cancers/mucoepidermoid-carcinoma/> .