# OnCo record fap (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/fap/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "fap" ;
  schema:name "FAP"@en ;
  schema:description "FAP (fibroblast activation protein) sits on the cancer-associated fibroblasts that scaffold more than 90% of epithelial cancers and is almost absent from normal adult tissue. FAPI PET tracers therefore light up tumours with high contrast, including pancreatic, gastric and low-grade cancers where FDG PET is weak, and FAP-targeted radioligands are in development."@en ;
  schema:url <https://onco.cc/targets/fap/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fibroblast_activation_protein,_alpha>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3590>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000078098>, <https://www.uniprot.org/uniprotkb/Q12884/entry>, <https://www.ncbi.nlm.nih.gov/gene/2191> ;
  owl:sameAs <http://www.wikidata.org/entity/Q21117471> ;
  schema:citation <https://en.wikipedia.org/wiki/Fibroblast_activation_protein,_alpha> ;
  onco:tag "theranostic", "pet-target", "stroma" ;
  schema:alternateName "FAP" ;
  onco:targetClass "stroma" ;
  onco:firstDescribed "1994"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/sarcoma/> ;
  onco:drugs <https://onco.cc/drugs/eb-mf-car-nk-01/> ;
  onco:companies <https://onco.cc/companies/ratio-therapeutics/> .