# OnCo record fgfr1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/fgfr1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "fgfr1" ;
  schema:name "FGFR1"@en ;
  schema:description "A growth receptor amplified in squamous lung cancer and fused in a rare blood cancer. Pemigatinib is approved for the FGFR1-rearranged myeloid and lymphoid neoplasm, and pan-FGFR drugs block FGFR1 too, which is why they raise blood phosphate."@en ;
  schema:url <https://onco.cc/targets/fgfr1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fibroblast_growth_factor_receptor_1>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3688>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000077782>, <https://www.uniprot.org/uniprotkb/P11362/entry>, <https://www.ncbi.nlm.nih.gov/gene/2260> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P11362/entry> ;
  schema:alternateName "FGFR1" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1988"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/pemigatinib/>, <https://onco.cc/drugs/erdafitinib/>, <https://onco.cc/drugs/futibatinib/> ;
  onco:pathways <https://onco.cc/pathways/fgfr-signalling/> ;
  onco:terms <https://onco.cc/terms/gene-amplification/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-weiss-fgfr1-amplification-squamous-lung-sci-transl-med-2010/> .