# OnCo record fgfr2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/fgfr2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "fgfr2" ;
  schema:name "FGFR2"@en ;
  schema:description "FGFR2 is a growth receptor fused in bile-duct cancer and overproduced in gastric cancer."@en ;
  schema:url <https://onco.cc/targets/fgfr2/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fibroblast_growth_factor_receptor_2>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3689>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000066468>, <https://www.uniprot.org/uniprotkb/P21802/entry>, <https://www.ncbi.nlm.nih.gov/gene/2263> ;
  owl:sameAs <http://www.wikidata.org/entity/Q14911644> ;
  schema:citation <https://en.wikipedia.org/wiki/Fibroblast_growth_factor_receptor_2> ;
  onco:tag "driver", "kinase" ;
  schema:alternateName "FGFR2" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1990"^^xsd:gYear ;
  onco:related <https://onco.cc/biomarkers/fgfr2-fusion-rearrangement/> ;
  onco:cancers <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gallbladder/> ;
  onco:drugs <https://onco.cc/drugs/therascreen-cdx/>, <https://onco.cc/drugs/hmpl-453/>, <https://onco.cc/drugs/tar-210/>, <https://onco.cc/drugs/tyra-300/>, <https://onco.cc/drugs/absk061/>, <https://onco.cc/drugs/cgt4859/>, <https://onco.cc/drugs/lirafugratinib/> ;
  onco:companies <https://onco.cc/companies/cogent-biosciences/>, <https://onco.cc/companies/relay-therapeutics/>, <https://onco.cc/companies/tyra-biosciences/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/fgfr-signalling/>, <https://onco.cc/pathways/gastric-cancer-signalling/> ;
  onco:trials <https://onco.cc/trials/nct05678270/>, <https://onco.cc/trials/nct06378593/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-philip-kras-wild-type-pancreatic-ccr-2022/>, <https://onco.cc/key-papers/paper-giraldo-gallbladder-msk-impact-ccr-2022/>, <https://onco.cc/key-papers/paper-nakamura-biliary-genomic-spectra-nat-genet-2015/>, <https://onco.cc/key-papers/paper-javle-biliary-ngs-cancer-2016/> .