# OnCo record fgl1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/fgl1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "fgl1" ;
  schema:name "FGL1"@en ;
  schema:alternateName "fibrinogen like 1"@en, "HFREP-1"@en, "hepassocin"@en, "FGL1" ;
  schema:description "FGL1 is a liver protein that some tumours secrete; it binds LAG-3 on T cells and switches them off, separately from the MHC class II route. It explains part of how LAG-3 blockade works."@en ;
  schema:url <https://onco.cc/targets/fgl1/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3695>, <https://www.uniprot.org/uniprotkb/Q08830/entry>, <https://www.ncbi.nlm.nih.gov/gene/2267> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "checkpoint" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3695>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104760>, <https://www.uniprot.org/uniprotkb/Q08830/entry>, <https://www.ncbi.nlm.nih.gov/gene/2267> ;
  onco:related <https://onco.cc/targets/lag3/>, <https://onco.cc/targets/hla-dra/>, <https://onco.cc/drugs/relatlimab-nivolumab/> ;
  onco:technologies <https://onco.cc/technologies/lag3-blockade/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/> .
