# OnCo record fh-deficient-renal-cell-carcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/fh-deficient-renal-cell-carcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "fh-deficient-renal-cell-carcinoma" ;
  schema:name "Fumarate hydratase-deficient renal cell carcinoma (HLRCC-associated)"@en ;
  schema:alternateName "FH-deficient renal cell carcinoma"@en, "Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma"@en, "HLRCC-associated RCC"@en, "Fumarate hydratase-deficient renal cell carcinoma (HLRCC syndrome)"@en, "Papillary renal cell carcinoma type 2 (former label for many cases)"@en ;
  schema:description "Fumarate hydratase-deficient renal cell carcinoma is a rare, aggressive kidney cancer in which the FH gene is lost, most often because the person was born with a faulty copy as part of the HLRCC syndrome, which also causes skin and womb fibroids. It strikes younger adults, is found by a stain for the missing enzyme, and needs family testing; advanced disease gets the usual kidney cancer drugs."@en ;
  schema:url <https://onco.cc/cancers/fh-deficient-renal-cell-carcinoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hereditary_leiomyomatosis_and_renal_cell_cancer_syndrome> ;
  schema:citation <https://www.cancer.gov/types/kidney/patient/kidney-treatment-pdq>, <https://doi.org/10.1016/j.eururo.2016.02.029>, <https://doi.org/10.1016/j.eururo.2022.06.016>, <https://doi.org/10.1097/pas.0000000000000617>, <https://doi.org/10.1097/pas.0000000000000719>, <https://doi.org/10.1111/his.13183> ;
  onco:tag "subtype-page", "wave4", "kidney", "rare" ;
  onco:related <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/papillary-rcc/>, <https://onco.cc/cancers/sdh-deficient-renal-cell-carcinoma/>, <https://onco.cc/cancers/collecting-duct-carcinoma/>, <https://onco.cc/cancers/hereditary-ppgl/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/fh/> ;
  onco:terms <https://onco.cc/terms/nephrectomy/>, <https://onco.cc/terms/hereditary-cancer-syndromes/> ;
  onco:standardOfCare <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/papillary-rcc/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/terms/nephrectomy/> .