# OnCo record ficerafusp-alfa (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ficerafusp-alfa/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ficerafusp-alfa" ;
  schema:name "Ficerafusp alfa"@en ;
  schema:description "Ficerafusp alfa is an EGFR antibody fused to a TGF-beta sponge, designed to remove the immune-suppressing signal that keeps HPV-negative throat cancers cold."@en ;
  schema:url <https://onco.cc/drugs/ficerafusp-alfa/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://ascopubs.org/doi/10.1200/JCO-25-02027> ;
  onco:status "phase-3" ;
  onco:modality "Bifunctional antibody (EGFR × TGF-β trap)" ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/recurrent-metastatic-hnscc/>, <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/> ;
  onco:targets <https://onco.cc/targets/egfr/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/> ;
  onco:companies <https://onco.cc/companies/bicara-therapeutics/> ;
  onco:trials <https://onco.cc/trials/fortifi-hn01/>, <https://onco.cc/trials/nct07807163/> .