# OnCo record filgrastim (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/filgrastim/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "filgrastim" ;
  schema:name "Filgrastim (G-CSF)"@en ;
  schema:alternateName "Zarxio (filgrastim-sndz)"@en, "Nivestym (filgrastim-aafi)"@en, "Releuko (filgrastim-ayow)"@en, "Granix (tbo-filgrastim)"@en, "Nypozi"@en, "Zarzio"@en, "Tevagrastim"@en, "Ratiograstim"@en, "Accofil"@en, "Grastofil"@en, "Neupogen" ;
  schema:description "Filgrastim (Neupogen and its biosimilars) is a daily injection that speeds the recovery of infection-fighting white cells after chemotherapy, lets doctors give chemotherapy on schedule and mobilises stem cells for transplant."@en ;
  schema:url <https://onco.cc/drugs/filgrastim/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Filgrastim> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=filgrastim>, <https://www.cancer.gov/about-cancer/treatment/drugs/filgrastim>, <https://www.ema.europa.eu/en/medicines/human/EPAR/zarzio> ;
  onco:status "approved" ;
  onco:tag "nci-list", "supportive" ;
  onco:modality "Recombinant granulocyte colony-stimulating factor" ;
  onco:approval "US 1991: Reduction of febrile neutropenia in non-myeloid malignancies on myelosuppressive chemotherapy; later AML induction, transplantation, stem cell mobilisation, severe chronic neutropenia", "US 2015: First US biosimilar (Zarxio, filgrastim-sndz); further biosimilars 2018 onwards", "EU 2008: First biosimilar filgrastims (Tevagrastim, Ratiograstim, Biograstim); Zarzio 2009" ;
  onco:related <https://onco.cc/drugs/pegfilgrastim/>, <https://onco.cc/drugs/plerixafor/> ;
  onco:technologies <https://onco.cc/technologies/g-csf-growth-factors/> ;
  onco:companies <https://onco.cc/companies/amgen/>, <https://onco.cc/companies/sandoz/>, <https://onco.cc/companies/teva/>, <https://onco.cc/companies/eurofarma/> ;
  onco:trials <https://onco.cc/trials/nct06212752/>, <https://onco.cc/trials/nct06514508/>, <https://onco.cc/trials/nct03246529/>, <https://onco.cc/trials/nct05722015/> .