# OnCo record flot4 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/flot4/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "flot4", "NCT01216644" ;
  schema:name "FLOT4-AIO"@en ;
  schema:alternateName "FLOT4"@en, "AIO-FLOT4"@en ;
  schema:description "FLOT4 showed that a docetaxel-based chemotherapy given before and after surgery helped people with operable stomach and junction cancers live longer than the older epirubicin-based regimen, and FLOT became the standard perioperative treatment in Europe."@en ;
  schema:url <https://onco.cc/trials/flot4/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01216644> ;
  onco:status "positive" ;
  onco:tag "subtype-trials" ;
  onco:phase "2/3" ;
  onco:cancers <https://onco.cc/cancers/oesophageal-adenocarcinoma/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/gastric/> ;
  onco:drugs <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/leucovorin/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/docetaxel/>, <https://onco.cc/drugs/epirubicin/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/capecitabine/> ;
  onco:people <https://onco.cc/people/salah-eddin-al-batran/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-flot4-lancet-2019/> .