# OnCo record flt3-tkd (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/flt3-tkd/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "flt3-tkd" ;
  schema:name "FLT3-TKD (D835 and I836 tyrosine kinase domain mutations)"@en ;
  schema:alternateName "FLT3-TKD"@en, "FLT3 TKD"@en, "FLT3 D835"@en, "FLT3 D835Y"@en, "FLT3 I836"@en, "FLT3 tyrosine kinase domain mutation"@en ;
  schema:description "FLT3-TKD mutations are point changes in the kinase's activation loop, found in about 7 percent of acute myeloid leukaemias. Midostaurin and gilteritinib labels cover them; quizartinib's does not."@en ;
  schema:url <https://onco.cc/biomarkers/flt3-tkd/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b5ff59aa-9c0d-49a8-9053-1f179b482383> ;
  onco:tag "biomarker", "flt3" ;
  onco:related <https://onco.cc/biomarkers/flt3-itd/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-flt3/> ;
  onco:drugs <https://onco.cc/drugs/midostaurin/>, <https://onco.cc/drugs/gilteritinib/>, <https://onco.cc/drugs/quizartinib/> ;
  onco:terms <https://onco.cc/terms/gatekeeper-mutation/> .