# OnCo record flt3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/flt3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "flt3" ;
  schema:name "FLT3"@en ;
  schema:description "FLT3 is a kinase mutated in about a third of acute myeloid leukaemias, where adding an inhibitor to chemotherapy improves survival."@en ;
  schema:url <https://onco.cc/targets/flt3/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CD135>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3765>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000122025>, <https://www.uniprot.org/uniprotkb/P36888/entry>, <https://www.ncbi.nlm.nih.gov/gene/2322> ;
  owl:sameAs <http://www.wikidata.org/entity/Q14912399> ;
  schema:citation <https://en.wikipedia.org/wiki/CD135> ;
  onco:tag "driver", "kinase" ;
  schema:alternateName "FLT3" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1991"^^xsd:gYear ;
  onco:related <https://onco.cc/biomarkers/flt3-itd/>, <https://onco.cc/biomarkers/flt3-tkd/> ;
  onco:cancers <https://onco.cc/cancers/aml/> ;
  onco:drugs <https://onco.cc/drugs/men1703/> ;
  onco:companies <https://onco.cc/companies/cullinan-therapeutics/> ;
  onco:pathways <https://onco.cc/pathways/aml-signalling/> .