# OnCo record fludarabine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/fludarabine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "fludarabine" ;
  schema:name "Fludarabine"@en ;
  schema:description "Fludarabine is a chemotherapy infusion for chronic lymphocytic leukaemia. It anchored the FCR regimen that was the first to give long remissions, and today it is used above all to prepare patients for CAR-T cells and transplants."@en ;
  schema:url <https://onco.cc/drugs/fludarabine/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fludarabine> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=fludarabine>, <https://www.cancer.gov/about-cancer/treatment/drugs/fludarabinephosphate> ;
  onco:status "approved" ;
  onco:tag "nci-list", "generic" ;
  onco:modality "Purine nucleotide analogue (antimetabolite)" ;
  schema:alternateName "Fludara (historic)" ;
  onco:approval "US 1991: B-cell chronic lymphocytic leukaemia after at least one alkylating-agent regimen" ;
  onco:acceleratedApproval "US 2008-12-18: For adults with B-cell CLL that has not responded to or progressed during or after treatment with at least one standard alkylating agent containing regimen" ;
  onco:cancers <https://onco.cc/cancers/cll/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/allogeneic-hsct/> ;
  onco:companies <https://onco.cc/companies/sanofi/> ;
  onco:trials <https://onco.cc/trials/nct06413498/>, <https://onco.cc/trials/nct06045806/>, <https://onco.cc/trials/nct05371093/>, <https://onco.cc/trials/nct07486089/>, <https://onco.cc/trials/nct06480565/>, <https://onco.cc/trials/nct04792489/>, <https://onco.cc/trials/nct06253663/>, <https://onco.cc/trials/nct05826535/>, <https://onco.cc/trials/nct07589543/>, <https://onco.cc/trials/nct07510815/>, <https://onco.cc/trials/nct03907852/>, <https://onco.cc/trials/nct07149857/>, <https://onco.cc/trials/nct07617805/>, <https://onco.cc/trials/nct06119685/>, <https://onco.cc/trials/nct07480928/>, <https://onco.cc/trials/nct04245839/>, <https://onco.cc/trials/nct06093841/>, <https://onco.cc/trials/nct04268706/>, <https://onco.cc/trials/nct07627711/>, <https://onco.cc/trials/nct04836507/>, <https://onco.cc/trials/nct07500220/>, <https://onco.cc/trials/nct07627698/>, <https://onco.cc/trials/nct07641036/>, <https://onco.cc/trials/nct07551349/>, <https://onco.cc/trials/nct04416984/>, <https://onco.cc/trials/nct07523529/>, <https://onco.cc/trials/nct07502287/>, <https://onco.cc/trials/nct07589530/>, <https://onco.cc/trials/nct05624554/>, <https://onco.cc/trials/nct03591510/>, <https://onco.cc/trials/nct07598955/>, <https://onco.cc/trials/nct07015242/>, <https://onco.cc/trials/nct06500273/>, <https://onco.cc/trials/nct03182244/>, <https://onco.cc/trials/nct03793478/>, <https://onco.cc/trials/nct07551362/> .