# OnCo record fmt-checkpoint-nonresponders (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/fmt-checkpoint-nonresponders/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "fmt-checkpoint-nonresponders" ;
  schema:name "Faecal microbiota transplantation for PD-1 non-responders"@en ;
  schema:description "Transplanting gut bacteria from patients who responded to immunotherapy into those who did not. In small studies a minority of resistant melanomas started responding. Randomised trials are running."@en ;
  schema:url <https://onco.cc/technologies/fmt-checkpoint-nonresponders/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fecal_microbiota_transplant> ;
  owl:sameAs <http://www.wikidata.org/entity/Q2121103> ;
  schema:citation <https://doi.org/10.1126/science.abf3363>, <https://doi.org/10.1038/s41591-023-02453-x> ;
  onco:status "phase-2" ;
  onco:related <https://onco.cc/ideas/idea-microbiome-io-fmt/>, <https://onco.cc/ideas/idea-bio2-fmt-plus-checkpoint-phase3/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/nutrition-lifestyle/>, <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/microbiome-modulation-io/>, <https://onco.cc/technologies/dietary-fibre-microbiome-io/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/nivolumab/> ;
  onco:pathways <https://onco.cc/pathways/microbiome-tumour/> ;
  onco:terms <https://onco.cc/terms/gut-microbiome-diversity/> ;
  onco:trials <https://onco.cc/trials/fmt-pd1-refractory-melanoma-pitt/>, <https://onco.cc/trials/mimic-01/> ;
  onco:people <https://onco.cc/people/laurence-zitvogel/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-davar-science/> .