# OnCo record fmt-pd1-refractory-melanoma-pitt (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/fmt-pd1-refractory-melanoma-pitt/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "fmt-pd1-refractory-melanoma-pitt", "NCT03341143" ;
  schema:name "FMT plus pembrolizumab in anti-PD-1-refractory melanoma (Pittsburgh)"@en ;
  schema:description "Fifteen melanoma patients whose immunotherapy had failed received a stool transplant from someone whose immunotherapy had worked, then restarted the drug. Six of them benefited, including three with lasting responses."@en ;
  schema:url <https://onco.cc/trials/fmt-pd1-refractory-melanoma-pitt/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03341143>, <https://doi.org/10.1126/science.abf3363>, <https://doi.org/10.1126/science.abb5920> ;
  onco:status "completed" ;
  onco:phase "2" ;
  schema:startDate "2018-03-19" ;
  onco:related <https://onco.cc/ideas/idea-microbiome-io-fmt/>, <https://onco.cc/ideas/idea-bio2-fmt-plus-checkpoint-phase3/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/> ;
  onco:sections <https://onco.cc/fronts/nutrition-lifestyle/>, <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/fmt-checkpoint-nonresponders/>, <https://onco.cc/technologies/microbiome-modulation-io/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/pembrolizumab/> ;
  onco:pathways <https://onco.cc/pathways/microbiome-tumour/> ;
  onco:terms <https://onco.cc/terms/gut-microbiome-diversity/>, <https://onco.cc/terms/orr/> ;
  onco:people <https://onco.cc/people/jennifer-wargo/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-davar-science/>, <https://onco.cc/key-papers/paper-baruch-science/> .