# OnCo record founder-variant (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/founder-variant/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "founder-variant" ;
  schema:name "Founder variant"@en ;
  schema:alternateName "founder mutation"@en, "founder mutations"@en, "founder variants"@en, "founder allele"@en, "founder alleles"@en, "founder effect"@en, "recurring founder variant"@en, "founder panel"@en ;
  schema:description "A disease-causing genetic change that is common in one population because many of its members descend from a small group of ancestors who happened to carry it. It says nothing about whether any particular person has it, and a negative founder test does not mean no inherited risk."@en ;
  schema:url <https://onco.cc/terms/founder-variant/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Founder_effect> ;
  schema:citation <https://doi.org/10.1186/s13053-023-00256-2>, <https://www.genome.gov/genetics-glossary/Founder-Effect>, <https://doi.org/10.1038/ejhg.2012.124>, <https://doi.org/10.1073/pnas.1415979111>, <https://doi.org/10.1007/s10549-010-1217-0> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/brca/> ;
  onco:terms <https://onco.cc/terms/vus/>, <https://onco.cc/terms/hereditary-cancer-syndromes/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-hereditary-risk/> .