# OnCo record foxo1-fusion-status (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/foxo1-fusion-status/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "foxo1-fusion-status" ;
  schema:name "FOXO1 fusion status and IRS group (rhabdomyosarcoma)"@en ;
  schema:alternateName "PAX3::FOXO1"@en, "PAX3-FOXO1"@en, "PAX7::FOXO1"@en, "PAX7-FOXO1"@en, "FOXO1 fusion"@en, "FOXO1 rearrangement"@en, "fusion-positive rhabdomyosarcoma"@en, "fusion-negative rhabdomyosarcoma"@en, "FP-RMS"@en, "FN-RMS"@en, "alveolar rhabdomyosarcoma"@en, "embryonal rhabdomyosarcoma"@en, "IRS group"@en, "IRS clinical group"@en, "Intergroup Rhabdomyosarcoma Study group"@en, "MYOD1 L122R"@en, "spindle cell sclerosing rhabdomyosarcoma"@en ;
  schema:description "Rhabdomyosarcoma used to be sorted by what it looked like (alveolar or embryonal); it is now sorted by whether the PAX3 or PAX7 gene is fused to FOXO1, because fusion-positive tumours relapse far more often whatever their appearance, and together with the surgical group and stage the fusion decides how intense treatment is."@en ;
  schema:url <https://onco.cc/terms/foxo1-fusion-status/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  onco:related <https://onco.cc/terms/gene-fusion/>, <https://onco.cc/terms/fish/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/dactinomycin/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/irinotecan/>, <https://onco.cc/terms/tp53-mutated/> ;
  onco:cancers <https://onco.cc/cancers/rhabdomyosarcoma/> .