# OnCo record foxtrot (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/foxtrot/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "foxtrot", "ISRCTN83842641" ;
  schema:name "FOxTROT"@en ;
  schema:alternateName "Fluoropyrimidine, Oxaliplatin and Targeted Receptor pre-Operative Therapy"@en, "ISRCTN83842641"@en ;
  schema:description "The UK trial that showed giving some chemotherapy before the operation for colon cancer shrinks the tumour, leaves cleaner margins and cuts the chance of the cancer coming back."@en ;
  schema:url <https://onco.cc/trials/foxtrot/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://europepmc.org/article/MED/36657089>, <https://europepmc.org/article/MED/39805350>, <https://www.isrctn.com/ISRCTN83842641> ;
  onco:status "positive" ;
  onco:tag "uk", "neoadjuvant", "colorectal", "platform" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/colon-cancer/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/>, <https://onco.cc/fronts/surgery/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/platinum/> ;
  onco:drugs <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/panitumumab/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:institutions <https://onco.cc/institutions/birmingham-cancer-centre/>, <https://onco.cc/institutions/leeds-cancer-centre/> ;
  onco:terms <https://onco.cc/terms/neoadjuvant-adjuvant/> ;
  onco:trials <https://onco.cc/trials/niche-2/> ;
  onco:people <https://onco.cc/people/dion-morton/>, <https://onco.cc/people/matt-seymour/> .