# OnCo record fractionation-repopulation-models (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/fractionation-repopulation-models/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "fractionation-repopulation-models" ;
  schema:name "The four Rs and accelerated repopulation"@en ;
  schema:description "Radiotherapy works through repair, redistribution, reoxygenation and repopulation between fractions; the discovery that tumours speed up their regrowth during a course explained why gaps in treatment cost cures and led to accelerated schedules."@en ;
  schema:url <https://onco.cc/technologies/fractionation-repopulation-models/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.3109/02841868809090333> ;
  onco:status "established" ;
  onco:tag "mathematical-model" ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/cervical/> ;
  onco:sections <https://onco.cc/fronts/ai-computation/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/linear-quadratic-model/>, <https://onco.cc/technologies/hypofractionated-radiotherapy/>, <https://onco.cc/technologies/imrt-igrt/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-withers-acta-oncol/> .