# OnCo record frk (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/frk/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "frk" ;
  schema:name "FRK kinase"@en ;
  schema:description "FRK is a SRC-related kinase that mostly acts as a brake on growth; it is a minor off-target of approved kinase inhibitors and is lost or mutated in some liver and brain cancers."@en ;
  schema:url <https://onco.cc/targets/frk/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/FRK_(gene)>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3955>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000111816>, <https://www.uniprot.org/uniprotkb/P42685/entry>, <https://www.ncbi.nlm.nih.gov/gene/2444> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P42685/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3955>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL4223> ;
  onco:tag "chembl-gap" ;
  schema:alternateName "FRK" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1993"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/src/> ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/hcc/> ;
  onco:drugs <https://onco.cc/drugs/dasatinib/> .