# OnCo record fruquintinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/fruquintinib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "fruquintinib" ;
  schema:name "Fruquintinib"@en ;
  schema:description "A Chinese-discovered pill that blocks the blood-vessel receptors, approved in 2023 for bowel cancer after all standard treatments."@en ;
  schema:url <https://onco.cc/drugs/fruquintinib/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Fruquintinib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q27259271> ;
  schema:citation <https://aacrjournals.org/clincancerres/article/30/15/3100/746597/FDA-Approval-Summary-Fruquintinib-for-the>, <https://www.nice.org.uk/guidance/ta1079>, <https://www.ema.europa.eu/en/medicines/human/EPAR/fruzaqla> ;
  onco:status "approved" ;
  onco:modality "Small-molecule kinase inhibitor (VEGFR1-3)" ;
  schema:alternateName "Fruzaqla" ;
  onco:approval "China 2018: Refractory mCRC (FRESCO)", "US 2023: Refractory mCRC after fluoropyrimidine, oxaliplatin, irinotecan, anti-VEGF, and anti-EGFR if appropriate", "EU 2024: Previously treated metastatic colorectal cancer", "England (NICE) 2025: Metastatic colorectal cancer at third line or later, only when trifluridine-tipiracil with bevacizumab is unsuitable" ;
  onco:cancers <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/antiangiogenic/> ;
  onco:targets <https://onco.cc/targets/vegf/> ;
  onco:companies <https://onco.cc/companies/takeda/> ;
  onco:trials <https://onco.cc/trials/fresco-2/>, <https://onco.cc/trials/nct06199973/>, <https://onco.cc/trials/nct06584032/>, <https://onco.cc/trials/nct06497985/>, <https://onco.cc/trials/nct07235293/>, <https://onco.cc/trials/nct05565417/>, <https://onco.cc/trials/nct06992258/>, <https://onco.cc/trials/nct05405595/>, <https://onco.cc/trials/nct05867420/>, <https://onco.cc/trials/fresco/> ;
  onco:people <https://onco.cc/people/su-weiguo/> .