# OnCo record gastric-cldn18-2-positive (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/gastric-cldn18-2-positive/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "gastric-cldn18-2-positive" ;
  schema:name "Claudin 18.2-positive gastric cancer"@en ;
  schema:alternateName "CLDN18.2-positive gastric cancer"@en, "Claudin 18.2-high gastro-oesophageal adenocarcinoma"@en ;
  schema:description "Claudin 18.2 is a tight-junction protein normally hidden inside stomach lining cells that becomes exposed on the surface of many stomach cancers. Zolbetuximab, an antibody against it, added to chemotherapy lengthens survival in tumours that express it strongly, and antibody-drug conjugates and CAR-T cells against the same target are in trials."@en ;
  schema:url <https://onco.cc/cancers/gastric-cldn18-2-positive/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Zolbetuximab> ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/37068504/>, <https://pubmed.ncbi.nlm.nih.gov/37524953/>, <https://en.wikipedia.org/wiki/Zolbetuximab> ;
  onco:tag "subtype-page" ;
  onco:pipeline <https://onco.cc/drugs/cmg901/>, <https://onco.cc/drugs/satricabtagene-autoleucel/>, <https://onco.cc/drugs/lm-302/>, <https://onco.cc/drugs/asp2138/>, <https://onco.cc/pairings/cldn18-antibody-then-adc/>, <https://onco.cc/ideas/idea-biomarker-quadruplet-gastric/> ;
  onco:standardOfCare <https://onco.cc/trials/spotlight-glow/>, <https://onco.cc/drugs/zolbetuximab/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/targets/cldn18-2/>, <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/ramucirumab/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/cmg901/>, <https://onco.cc/drugs/satricabtagene-autoleucel/>, <https://onco.cc/pairings/cldn18-antibody-then-adc/>, <https://onco.cc/drugs/zolbetuximab/> .