# OnCo record gastric-her2-positive (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/gastric-her2-positive/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "gastric-her2-positive" ;
  schema:name "HER2-positive gastric cancer"@en ;
  schema:alternateName "HER2-positive gastro-oesophageal adenocarcinoma"@en, "ERBB2-amplified gastric cancer"@en, "HER2+ GEA"@en ;
  schema:description "HER2-positive gastric cancer overexpresses the HER2 growth receptor and is treated with trastuzumab added to chemotherapy, now usually with pembrolizumab as well. After progression the antibody-drug conjugate trastuzumab deruxtecan gives responses that plain chemotherapy cannot."@en ;
  schema:url <https://onco.cc/cancers/gastric-her2-positive/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Stomach_cancer> ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/20728210/>, <https://www.nejm.org/doi/full/10.1056/NEJMoa2004413>, <https://en.wikipedia.org/wiki/Stomach_cancer> ;
  onco:tag "subtype-page" ;
  onco:pipeline <https://onco.cc/drugs/zanidatamab/>, <https://onco.cc/trials/herizon-gea-01/>, <https://onco.cc/drugs/disitamab-vedotin/>, <https://onco.cc/pairings/her2-gastric-sequence/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/> ;
  onco:standardOfCare <https://onco.cc/trials/toga/>, <https://onco.cc/drugs/trastuzumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/capecitabine/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/targets/her2/>, <https://onco.cc/pairings/her2-gastric-sequence/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/>, <https://onco.cc/trials/destiny-gastric04/>, <https://onco.cc/drugs/ramucirumab/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/trifluridine-tipiracil/>, <https://onco.cc/drugs/zanidatamab/>, <https://onco.cc/trials/herizon-gea-01/>, <https://onco.cc/drugs/flot/>, <https://onco.cc/terms/gastrectomy/> .