# OnCo record gefitinib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: .
@prefix onco: .
@prefix owl: .
@prefix xsd: .
a schema:Drug ;
onco:kind "drug" ;
schema:identifier "gefitinib" ;
schema:name "Gefitinib"@en ;
schema:description "The lung-cancer pill whose dramatic responses in a few patients led to the discovery of EGFR mutations in 2004."@en ;
schema:url ;
schema:dateModified "2026-09-08"^^xsd:date ;
schema:sameAs ;
owl:sameAs ;
schema:citation , ;
onco:status "approved" ;
onco:tag "gap-fill", "generic" ;
onco:modality "Small-molecule EGFR TKI (first generation, reversible)" ;
schema:alternateName "Iressa" ;
onco:approval "US 2003: NSCLC after chemotherapy (accelerated; restricted 2005)", "EU 2009: EGFR-mutant NSCLC", "US 2015: First-line NSCLC with EGFR exon 19 del or L858R" ;
onco:acceleratedApproval "US 2003-05-05: As monotherapy for locally advanced or metastatic NSCLC after failure of platinum-based and docetaxel chemotherapy" ;
onco:related ;
onco:cancers , ;
onco:technologies ;
onco:targets ;
onco:companies ;
onco:terms , ;
onco:trials , , , ;
onco:keyPapers .