# OnCo record geneformer (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/geneformer/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "geneformer" ;
  schema:name "Geneformer"@en ;
  schema:description "Geneformer is a transformer trained on about 30 million single cells that encodes each cell as a ranked list of its genes, so deleting a gene in silico shows which genes matter in a disease. It was the first single-cell foundation model in general use, though benchmarks find only modest gains over linear baselines on some tasks."@en ;
  schema:url <https://onco.cc/technologies/geneformer/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41586-023-06139-9> ;
  onco:status "emerging" ;
  onco:tag "foundation-model", "virtual-cell" ;
  onco:related <https://onco.cc/roadmaps/virtual-cell/> ;
  onco:sections <https://onco.cc/fronts/ai-computation/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/single-cell-spatial/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-theodoris-nature/> .
