# OnCo record genome-wide-ctdna-mutation-integration (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/genome-wide-ctdna-mutation-integration/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "genome-wide-ctdna-mutation-integration" ;
  schema:name "Genome-wide ctDNA mutation integration (MRDetect, MRD-EDGE)"@en ;
  schema:alternateName "MRDetect"@en, "MRD-EDGE"@en, "Whole-genome ctDNA MRD"@en ;
  schema:description "Instead of reading a few of the tumour's mutations very deeply in blood, read the whole genome once and add up the faint signal from thousands of mutations."@en ;
  schema:url <https://onco.cc/technologies/genome-wide-ctdna-mutation-integration/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-020-0915-3>, <https://doi.org/10.1038/s41591-024-03040-4> ;
  onco:status "emerging" ;
  onco:related <https://onco.cc/drugs/accuscan-mrd/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/mrd-testing/>, <https://onco.cc/technologies/wes-wgs/> ;
  onco:drugs <https://onco.cc/drugs/truemrd/> ;
  onco:terms <https://onco.cc/terms/ctdna/>, <https://onco.cc/terms/cfdna/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-subclone-attribution-residual-disease/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-zviran-whole-genome-cfdna-residual-disease-nat-med-2020/>, <https://onco.cc/key-papers/paper-widman-mrd-edge-nat-med-2024/> .