# OnCo record germline-brca-testing-criteria-tnbc (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/germline-brca-testing-criteria-tnbc/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "germline-brca-testing-criteria-tnbc" ;
  schema:name "Germline BRCA testing criteria for triple-negative breast cancer (UK)"@en ;
  schema:alternateName "Who gets BRCA testing"@en, "Mainstream genetic testing criteria"@en, "NICE genetic testing threshold 10 percent"@en, "TNBC under 50 BRCA testing"@en, "TNBC under 60 testing"@en, "Manchester score"@en, "R208 testing criteria"@en ;
  schema:description "In the NHS a blood test for inherited BRCA1 and BRCA2 faults is offered to every woman under 50 with triple-negative breast cancer, whatever her family history, and hospital testing criteria now extend that to triple-negative disease under 60 and any breast cancer under 40. Others are tested when a calculator puts the chance of a family fault at 10 percent or more."@en ;
  schema:url <https://onco.cc/terms/germline-brca-testing-criteria-tnbc/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/BRCA_mutation> ;
  schema:citation <https://www.nice.org.uk/guidance/ng101/chapter/Recommendations>, <https://www.nice.org.uk/guidance/cg164/chapter/Recommendations>, <https://doi.org/10.1016/j.gimo.2023.100849>, <https://doi.org/10.1200/jco.2014.57.1414>, <https://doi.org/10.1007/s10549-014-2980-0>, <https://www.cancerresearchuk.org/about-cancer/breast-cancer/risks-causes/family-history-and-inherited-genes>, <https://www.nice.org.uk/guidance/ta886> ;
  onco:tag "breast", "tnbc" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/brca-associated-tnbc/>, <https://onco.cc/cancers/tnbc-early/>, <https://onco.cc/cancers/breast-cancer/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/brca/> ;
  onco:terms <https://onco.cc/terms/germline-vs-somatic/>, <https://onco.cc/terms/risk-reducing-surgery-brca-carriers/> .