# OnCo record giredestrant (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/giredestrant/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "giredestrant" ;
  schema:name "Giredestrant"@en ;
  schema:description "Giredestrant is Roche's oral SERD: it failed to beat an aromatase inhibitor in first-line metastatic disease but succeeded after surgery and after CDK4/6 failure."@en ;
  schema:url <https://onco.cc/drugs/giredestrant/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05306340> ;
  onco:status "phase-3" ;
  onco:modality "Oral SERD" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/oral-serd/> ;
  onco:trials <https://onco.cc/trials/evera/>, <https://onco.cc/trials/lidera/>, <https://onco.cc/trials/persevera/>, <https://onco.cc/trials/nct07100106/>, <https://onco.cc/trials/nct06065748/>, <https://onco.cc/trials/nct05296798/>, <https://onco.cc/trials/nct07541079/>, <https://onco.cc/trials/nct04576455/>, <https://onco.cc/trials/nct07054190/> .