# OnCo record glasdegib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/glasdegib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "glasdegib" ;
  schema:name "Glasdegib"@en ;
  schema:description "Glasdegib is a hedgehog-pathway pill that, with low-dose chemotherapy, extends survival in older AML patients who cannot have intensive treatment; it has largely been displaced by venetoclax combinations."@en ;
  schema:url <https://onco.cc/drugs/glasdegib/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Glasdegib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q27077810> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=glasdegib> ;
  onco:status "approved" ;
  onco:tag "gap-fill" ;
  onco:modality "Small-molecule smoothened (hedgehog) inhibitor" ;
  schema:alternateName "Daurismo" ;
  onco:approval "US 2018: Newly diagnosed AML in adults ≥75 or unfit for intensive chemotherapy, with low-dose cytarabine", "EU 2020: Same" ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/aml-older-unfit/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/hedgehog-inhibitors/> ;
  onco:targets <https://onco.cc/targets/smoothened/> ;
  onco:companies <https://onco.cc/companies/pfizer/> ;
  onco:trials <https://onco.cc/trials/nct03416179/>, <https://onco.cc/trials/nct04842604/>, <https://onco.cc/trials/nct04093505/> .