# OnCo record glioma-car-t (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/glioma-car-t/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "glioma-car-t" ;
  schema:name "CAR-T for glioma (IL13Rα2, GD2, EGFRvIII, multi-target)"@en ;
  schema:description "Engineered immune cells delivered directly into the brain or spinal fluid. Some children with diffuse midline glioma, a brainstem tumour with no curative treatment, have had striking, if temporary, responses."@en ;
  schema:url <https://onco.cc/technologies/glioma-car-t/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41586-022-04489-4>, <https://doi.org/10.1056/NEJMoa1610497> ;
  onco:status "phase-1" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/>, <https://onco.cc/cancers/neuroblastoma/> ;
  onco:sections <https://onco.cc/fronts/cell-therapy/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/armored-car/> ;
  onco:targets <https://onco.cc/targets/egfr/> ;
  onco:institutions <https://onco.cc/institutions/city-of-hope/>, <https://onco.cc/institutions/stanford/>, <https://onco.cc/institutions/mgh/>, <https://onco.cc/institutions/penn-abramson/> ;
  onco:terms <https://onco.cc/terms/h3k27m/>, <https://onco.cc/terms/egfrviii/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-majzner-nature/>, <https://onco.cc/key-papers/paper-brown-n-engl-j-med/> .