# OnCo record glucocorticoid-receptor (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/glucocorticoid-receptor/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "glucocorticoid-receptor" ;
  schema:name "Glucocorticoid receptor (NR3C1)"@en ;
  schema:description "The receptor that steroid hormones switch on inside cells. In lymphoid cancers, dexamethasone and prednisone acting through it kill malignant lymphocytes directly, which is why steroids sit inside leukaemia, lymphoma and myeloma regimens as well as easing nausea and swelling."@en ;
  schema:url <https://onco.cc/targets/glucocorticoid-receptor/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Glucocorticoid_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7978>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000113580>, <https://www.uniprot.org/uniprotkb/P04150/entry>, <https://www.ncbi.nlm.nih.gov/gene/2908> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P04150/entry> ;
  schema:alternateName "NR3C1" ;
  onco:targetClass "nuclear-receptor" ;
  onco:firstDescribed "1985"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/hodgkin-lymphoma/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:drugs <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/prednisone/> .