# OnCo record glutamine-metabolism (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/glutamine-metabolism/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "glutamine-metabolism" ;
  schema:name "Glutamine addiction"@en ;
  schema:description "After glucose, glutamine is the tumour's favourite food. It feeds the energy cycle, donates nitrogen for making DNA letters, and makes the antioxidant glutathione. MYC- and KRAS-driven cancers eat so much of it that they starve the T cells next door."@en ;
  schema:url <https://onco.cc/pathways/glutamine-metabolism/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Glutaminolysis> ;
  schema:citation <https://doi.org/10.1038/nrc.2016.71> ;
  onco:tag "mechanism", "mechanics-atlas" ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/metabolic-therapy/>, <https://onco.cc/technologies/fdg-pet/>, <https://onco.cc/technologies/pet/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/idh/>, <https://onco.cc/targets/akt/>, <https://onco.cc/targets/pd1/> ;
  onco:drugs <https://onco.cc/drugs/asparaginase/>, <https://onco.cc/drugs/ivosidenib/>, <https://onco.cc/drugs/vorasidenib/> ;
  onco:pathways <https://onco.cc/pathways/cancer-metabolism/>, <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/keap1-nrf2/>, <https://onco.cc/pathways/nutrient-competition-tme/> ;
  onco:terms <https://onco.cc/terms/warburg-effect/>, <https://onco.cc/terms/deregulating-cellular-energetics/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-altman-nat-rev-cancer/> .