# OnCo record gnrhr (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/gnrhr/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "gnrhr" ;
  schema:name "GnRH receptor (GNRHR)"@en ;
  schema:description "The pituitary receptor that starts the hormone chain leading to testosterone and oestrogen. Agonists overstimulate it into silence and antagonists block it outright, the basis of medical castration in prostate cancer and ovarian suppression in breast cancer."@en ;
  schema:url <https://onco.cc/targets/gnrhr/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Gonadotropin-releasing_hormone_receptor>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4421>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000109163>, <https://www.uniprot.org/uniprotkb/P30968/entry>, <https://www.ncbi.nlm.nih.gov/gene/2798> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P30968/entry> ;
  schema:alternateName "GNRHR" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1992"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:drugs <https://onco.cc/drugs/leuprolide/>, <https://onco.cc/drugs/goserelin/>, <https://onco.cc/drugs/degarelix/> .