# OnCo record goldie-coldman-model (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/goldie-coldman-model/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "goldie-coldman-model" ;
  schema:name "Goldie-Coldman model of resistance"@en ;
  schema:description "Resistant cells arise by chance mutation as a tumour grows, so the chance of a cancer already containing resistant cells rises with its size. The model argued for treating early and for alternating non-cross-resistant drugs."@en ;
  schema:url <https://onco.cc/technologies/goldie-coldman-model/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://pubmed.ncbi.nlm.nih.gov/526911/> ;
  onco:status "established" ;
  onco:tag "mathematical-model" ;
  onco:sections <https://onco.cc/fronts/ai-computation/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/drug-resistance-dynamics/>, <https://onco.cc/technologies/clonal-evolution-tracking/> .