# OnCo record gpr65 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/gpr65/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "gpr65" ;
  schema:name "GPR65"@en ;
  schema:alternateName "G protein-coupled receptor 65"@en, "TDAG8"@en, "GPR65" ;
  schema:description "GPR65 is a sensor on immune cells that detects acidity. Tumours are often acidic, and the idea behind blocking GPR65 is to stop that acidity from turning nearby immune cells into ones that help the tumour; a GPR65 inhibitor is in an early trial."@en ;
  schema:url <https://onco.cc/targets/gpr65/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4517>, <https://www.uniprot.org/uniprotkb/Q8IYL9/entry>, <https://www.ncbi.nlm.nih.gov/gene/8477>, <https://doi.org/10.3389/fphys.2013.00354>, <https://doi.org/10.1016/j.bbadis.2021.166288> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4517>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000140030>, <https://www.uniprot.org/uniprotkb/Q8IYL9/entry>, <https://www.ncbi.nlm.nih.gov/gene/8477> ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:drugs <https://onco.cc/drugs/ptt-4256/> .