# OnCo record griffin-nucleosome-profiling (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/griffin-nucleosome-profiling/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "griffin-nucleosome-profiling" ;
  schema:name "Griffin (nucleosome profiling of cell-free DNA)"@en ;
  schema:alternateName "Griffin"@en ;
  schema:description "A way of reading which genes are switched on in a tumour from the pattern of where DNA in the blood is protected, used to tell whether a breast cancer still carries the oestrogen receptor."@en ;
  schema:url <https://onco.cc/technologies/griffin-nucleosome-profiling/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41467-022-35076-w> ;
  onco:status "emerging" ;
  onco:related <https://onco.cc/technologies/meter-methylome-subtyping/>, <https://onco.cc/technologies/epic-seq/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/> ;
  onco:technologies <https://onco.cc/technologies/fragmentomics/>, <https://onco.cc/technologies/liquid-biopsy/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:terms <https://onco.cc/terms/cfdna/>, <https://onco.cc/terms/ctdna/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-subclone-attribution-residual-disease/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-doebley-griffin-nucleosome-profiling-nat-commun-2022/> .